Cardiovascular mortality is inversely related to wine consumption

Globally, cardiovascular diseases (CVDs) account for a significant part of mortality, with IHD accounting for about half of the nearly 18 million CVD-related deaths in 2017.

Source

According to a prior meta-analysis, there is a J-shaped correlation between moderate wine consumption and a lower risk of cardiovascular events.

Researchers also claimed that several wine components have protective benefits against pathologies including coronary heart diseases, CHD-associated mortality, and cancers like oral cancer in their initial 1979 paper on the beneficial effects of wine on CVDs.

Furthermore,research has suggested that non-alcoholic wines (in the absence of ethanol) may provide protection against thrombosis due to their ability to maintain antioxidant effects.

Having a moderate amount of alcohol in moderation can have a positive impact on general health as it actively lowers levels of bad cholesterol while increasing good cholesterol which in turn reduces the incidence of ischemic heart disease.

However, excessive consumption of alcohol leads to more than 200 diseases, which therefore makes it one of the leading causes worldwide resulting in up to three million deaths annually. As per psychiatrists, consuming excessive amounts of alcohol increases the likelihood of suicide.

The presence of various drugs can impact how alcohol is metabolized or its own physiological effects, which could potentially result in higher blood alcohol levels. Just like that, resveratrol-a component present in wine-interacts with specific medications and adjusts their metabolism.

Red wine is rich in non-flavonoid polyphenols like tannins which offer multiple benefits for cardiovascular health. In addition to being anti-inflammatory, It serves as an antioxidant and displays antimutagenic properties, excessive alcohol consumption increases the risk of CHD mortality as well as cancers and so on.

Mendelian randomization analysis explored how alcohol consumption affects CVDs and revealed that individuals with the ADH1B gene experience a significant decrease in CHD risk when they reduce their alcohol intake.

Likewise, research suggests that wine intake can have a favorable impact on nonfatal CHD, whereas consuming beer may lead to an increased risk of suffering from a nonfatal stroke. Researchers suggest based on these observations that wine components might benefit health.

The researchers may have assumed that all alcoholic beverages had similar beneficial effects on cardiac health because they never stratified these effects by the type of alcohol. The researchers assumed that all alcoholic drinks had comparable positive impacts on heart health. However, the available scientific evidence does not clearly indicate which alcoholic beverages could be less harmful to CVDs.