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You see we humans are aware of the manner at which the body adapts to substances but we just don't get the full gist of it. For instance, for those that take alcohol, after a long period of time, their alcohol tolerance increases but people consider it to be a good thing, like a skill but when our body develops high tolerance for medications, it is a problem.
It is a little bit ironic, the body always adapts to things every single day, we just don't notice.
Yes, you are very right. The body adapts to things but we don't notice until there is an issue.